304am永利集团官方网站欢迎您的光临！
免费咨询热线： 4008-750-250
科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CRFR2b/CHO
| CBP71436 | |
| I. Background | |
| The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. | |
| II. Introduction | |
| Host Cell: |
CHO |
| Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Expressed Gene: | CRFR2b |
| Synonym(s): | CRFR2 | CRF-R2 | CRH-R2 | CRF 2 receptor | CRFR2alpha | CRFR2beta |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | N/A |
| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): |
Functional assay for CRFR2b receptor |
| Transducer: | Gs family |
| Ⅲ. Description of Host Cell Line | |
| Organism: | Hamster |
| Tissue: | Ovary |
| Morphology: | Epithelial |
| Growth Properties: | Adherent |
| Ⅳ. Representative Data | |
|
Figure 1. HTRF cAMP Assay With CRFR2b CHO Cells(C11). |
|
扫一扫，关注我们公众号
Copyright ©2021 www.cobioer.com All Rights Reserved. 304am永利集团版权所有 苏ICP备13038923号