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索取COA
产品描述
产品数据库
Introduction | |
Format | Genomic DNA |
Description | BRCA1 E23Vfs*17 (also referred to as BRCA1 185delAG) indicates a shift in the reading frame starting at amino acid 23 and terminating 17 residues downstream causing a premature truncation of the 1863 amino acid Brca1 protein (UniProt.org). E23Vfs*17 confers a loss of function to the Brca1 protein as indicated by embryonic lethality in homozygous transgenic mouse models and tumorigenesis in heterozygous transgenic mouse models (PMID: 27454287). |
Technical Data | |
DNA Change | c.66_67delAG |
AA Change | p.E23fs*17 |
Mutation type | Deletion - Frameshift |
Zygosity | Heterozygous |
Allelic Frequency | 100% |
Transcript | ENST00000357654 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr17:41276045_41276046 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 2-8°C |
Expiry | 36 months from the date of manufacture |