CTNNB1 p.S37F Reference Standard

CBP10253

询价

索取COA

产品描述

产品数据库

Introduction
Format	Genomic DNA
Description	CTNNB1 S37F lies within the ubiquitination recognition motif of the Ctnnb1 protein and occurs at a Gsk3b phosphorylation site on the Ctnnb1 protein (PMID: 10347231). S37F is predicted to confer a gain of function to the Ctnnb1 protein as demonstrated by nuclear accumulation of Ctnnb1 (PMID: 11196159, PMID: 11943721) and increased cell invasion and migration in the context of an EGFR activating mutation (PMID: 29106415).

Technical Data
DNA Change	c.110C>T
AA Change	p.S37F
Mutation type	Substitution - Missense
Zygosity	Heterozygous
Allelic Frequency	50.00%
Transcript	ENST00000349496
Cosmic ID	COSM5662
Chr position(GRCh37)	chr3:41266113
Buffer	Tris-EDTA

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing
Storage	2-8℃
Expiry	36 months from the date of manufacture

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