TP53 p.G389W Reference Standard

CBP10529

询价

索取COA

产品描述

产品数据库

Introduction
Format	Genomic DNA
Description	TP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457).

Technical Data
DNA Change	c.1165G>T
AA Change	p.G389W
Mutation type	Missense_Mutation
Zygosity	Heterozygous
Allelic Frequency	50%
Transcript	ENST00000269305.4
Cosmic ID	N/A
Chr position(GRCh37)	chr17:7572944
Buffer	Tris-EDTA

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing
Storage	2-8°C
Expiry	36 months from the date of manufacture

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