TP53 p.N239D Reference Standard
CBP10204
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| Introduction | |
| Format | Genomic DNA |
| Description | TP53 N239D lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). N239D results in a loss of Tp53 transactivation activity in a yeast assay (PMID: 20407015), but has not been characterized in human cells and therefore its effect on Tp53 protein function is unknown. |
| Technical Data | |
| DNA Change | c.715A>G |
| AA Change | p.N239D |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 66.67% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10777 |
| Chr position(GRCh37) | chr17:7577566 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
