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Introduction | |
Format | Genomic DNA |
Description | TP53 V31I lies within the CCAR2 and HRMT1L2-interacting regions and the transcription activation region of the Tp53 protein (UniProt.org). V31I results in colony growth, induction of apoptosis, and transcriptional activity similar to wild-type Tp53 in cultured cells (PMID: 33257846), and therefore, is predicted to have no effect on Tp53 protein function. |
Technical Data | |
DNA Change | c.91G>A |
AA Change | p.V31I |
Mutation type | Substitution - Missense |
Zygosity | N/A |
Allelic Frequency | N/A |
Cosmic ID | COSM45360 |
Chr position(GRCh37) | chr17:7579705 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | 2-8℃ |
Expiry | 36 months from the date of manufacture |