PTEN p.K6Rfs*4 Reference Standard

CBP10719

询价

索取COA

产品描述

产品数据库

Introduction
Gene	PTEN
Description	PTEN, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, is a tumor suppressor with roles in the cell cycle, growth, DNA repair, cell survival and regulation of the Akt-mTOR pathway. PTEN germline mutations are common in Cowden syndrome and PTEN somatic alterations resulting in loss of function have been found in many types of cancer including, but not limited to endometrial , melanoma, and prostate.

Technical Data
DNA Change	c.17_18del
AA Change	p.K6Rfs*4
Mutation type	Deletion - Frameshift
Zygosity	Homozygous
Allelic Frequency	100%
Transcript	ENST00000371953.3
Cosmic ID	COSM4929
Chr position	chr10-87864485-AA-_hg38
Buffer	Tris-EDTA

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing
Storage	2-8℃
Expiry	36 months from the date of manufacture

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