GPR120/CHO
CBP71105
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I. Background | |
GPR120 is a GPCR that responds to long-chain FAs. This receptor was recently shown to be expressed in macrophages, where it is coupled to the β-arrestin pathway. | |
II. Introduction | |
Host Cell: |
CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | N/A |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): |
Functional assay for GPR120 receptor |
Transducer: | Gq/G11 family |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1.Dose Response of TUG-891 in GPR120 CHO Cells (C1). |