CSF3R WT/BaF3
CBP73264
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I. Introduction | |
Cell Line Name: |
CSF3R WT/BaF3 |
Host Cell: |
Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: |
Anti-proliferation assay and PD assay |
Freeze Medium: |
90% FBS+10% DMSO |
Complete Culture Medium: |
RPMI-1640+10%FBS |
Mycoplasma Status: |
Negative |
II. Background | |
CSF3R, colony stimulating factor 3 receptor, encodes a cytokine receptor regulating proliferation and differentiation of myeloid progenitor cells (PMID: 27789332). CSF3R mutations commonly occur in chronic neutrophilic leukemia and acute myeloid leukemia (PMID: 23896413, PMID: 30348809). |
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III. Representative Data | |
1.WB of CSF3R WT/BaF3
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2. Anti-proliferation assay
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R WT/BaF3. |