FGFR2-AHCYL1/BaF3
CBP73267
I. Introduction | |
Cell Line Name: |
FGFR2-AHCYL1/BaF3 |
Host Cell: |
Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: |
Anti-proliferation assay and PD assay |
Freeze Medium: |
90% FBS+10% DMSO |
Complete Culture Medium: |
RPMI-1640+10%FBS+2ug/ml puromycin |
Mycoplasma Status: |
Negative |
II. Background | |
FGFR2-AHCYL1 results from the fusion of FGFR2 and AHCYL1, resulting in the ability to activate MAPK signaling and induce transformation of cells in culture and in animal models (PMID: 24122810). FGFR2-AHCYL1 has been identified in intrahepatic cholangiocarcinoma (PMID: 24122810). |
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III. Representative Data | |
1. WB of FGFR2-AHCYL1/BaF3
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2. Sanger of FGFR2-AHCYL1/BaF3
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3. Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 FGFR2-AHCYL1 Cells(C1). |
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