SW1116(人结肠腺癌细胞)
CBP60748
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I. General information | |
Synonyms: | SW1116 |
Species: | Homo sapiens, human |
Tissue: | colon adenocarcinoma |
Disease: | Dukes' type A, grade III, colorectal adenocarcinoma |
Gender: | male,73 years,Caucasian |
Morphology: | epithelial |
Growth Mode: | adherent |
DNA Profile: | Amelogenin: X,Y CSF1PO: 10,11 D13S317: 11,14 D16S539: 9,12 D5S818: 11,12 D7S820: 12 THO1: 6 TPOX: 8,11 vWA: 14,19 Cobioer’s Cell Line Authentication Service |
Culture Medium: |
MEM + 20% Foetal Bovine Serum (FBS)+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) We strongly suggest to purchase the complete medium from Cobioer. |
Cryopreservation medium: | 90%FBS+10%DMSO |
Antigen Expression: | blood type O, Rh+ |
Oncogene: | myc +; myb + ; ras +; fos +; sis +; p53 +; abl -; ros -; src - |
Genes Expressed: | carcinoembryonic antigen (CEA) 2654 ng/106 cells/10 days; keratin |
Tumor Formation: | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 10(7) cells) |
Comments: | CSAp negative (CSAp-). Colon antigen 3, negative. The cells are positive for keratin by immunoperoxidase staining. The line is positive for expression of c-myc, K-ras, H-ras, myb, sis and fos oncogenes. N-myc and N-ras oncogene expression were not detected. Tumor specific nuclear matrix proteins CC-4, CC-5 and CC-6 are expressed. For more information, please contact Cobioer (4008-750-250). |