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AI-Edigene® EGFR p.G719S Reference Standard Plus

CBP10511

询价

索取COA

产品描述

产品数据库

Introduction
Format	Genomic DNA
Description	EGFR G719S lies within the phosphate-binding “P loop” in the protein kinase domain of the Egfr protein (PMID: 17349580). G719S results in constitutive ligand-independent phosphorylation of Egfr, activation of Stat5, Erk1/2, and Akt, and is transforming in cell culture (PMID: 16204070, PMID: 24894453, PMID: 18573086, PMID: 29533785).

Technical Data
DNA Change	c.2155G>A
AA Change	p.G719S
Mutation type	Substitution - Missense
Zygosity	Homozygous
Allelic Frequency	100%
Transcript	ENST00000275493
Cosmic ID	COSM6252
Chr position(GRCh37)	chr7:55241707
Buffer	Tris-EDTA

Product Information
Intended Use	Research Use Only
Unit Size	1ug
Concentration	Download for COA
Purofication	Download for COA
DNA electrophoresis	Download for COA
Sanger sequencing
Storage	2-8℃
Expiry	36 months from the date of manufacture

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