EGFR p.G598V Reference Standard
CBP10266
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| Introduction | |
| Format | Genomic DNA |
| Description | EGFR G598V lies within the extracellular domain of the Egfr protein (UniProt.org). G598V results in increased Egfr activity (PMID: 17177598), is transforming in cell culture (PMID: 29533785), and promotes tumor formation in mice (PMID: 17177598). |
| Technical Data | |
| DNA Change | c.1793G>T |
| AA Change | p.G598V |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000275493 |
| Cosmic ID | COSM21690 |
| Chr position(GRCh37) | chr7:55233043 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
