KRAS G12D/BaF3
CBP73228
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| I. Introduction | |
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Cell Line Name： |
KRAS G12D/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Application: |
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Freeze Medium: | 90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS+1ug/ml puromycin |
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Mycoplasma Status: |
Negative |
| II. Background | |
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KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). |
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| III. Representative Data | |
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1.WB of KRAS G12D/BaF3
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2.Sanger of KRAS G12D/BaF3
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3. Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 KRAS G12D Cells (C6). |
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