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Rat SSTR2/CHO

CBP71428

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I. Background
Somatostatin, a pivotal signaling peptide involved in multifarious physiological processes, exerts its influence through five somatostatin receptor subtypes (SSTR 1–5). Among these, SSTR2 stands as the most prevalent in normative tissues and is conspicuously overexpressed in a variety of solid tumors. Located on the long arm of chromosome 17, SSTR2 yields an expansive spectrum of biological impacts, including the regulation of neurotransmission and secretion, as well as the inhibition of tumor cell proliferation .
 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assays for Rat SSTR2

Transducer: Gi
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data
 

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